Acne Treatment Medication - Medications Cause Acne
 

Acne Treatment Medication


Medications:
Some medications are known to cause acne. Some cortisones, few anti-tuberculosis drugs (isoniazid and rifampin) and some anti-epileptic drugs and anti-seizure medications (Example: Dilantin; Kapseals) can cause acne. Chlorinated solvents can also cause occupational acne. Also medications that include anabolic steroids (sometimes used illegally by athletes to “bulk up”), and lithium and iodine-containing medications.


Hormone medications like contraceptive agents [medroxyprogesterone injections (Depo-Provera) and older oral contraceptives -newer birth control pills such as Ortho Tri-Cyclen and Estrostep can actually improve acne-, testosterone, corticosteroids [prednisone, methylprednisone, dexamethasone, prednisolone, betamethasone, cortisone, hydrocortisone, and triamcinolone], and anabolic steroids [danocrine (Danazol) and stanozolol (Stomba)] can all make acne worse. Other medications known to exacerbate acne include certain antidepressants, , and cyclosporin (Neoral, Sandimmune).


Thyroid Medications: Prescribed to stimulate the thyroid gland in patients with low thyroid function. Acne is a side effect.
Example: Propylthiouracil.

Disulfuram - prescribed for alcoholic patients trying to achieve sobriety. Regular use can trigger acne.
Example: Antabuse.

Immunosuppressants - prescribed to suppress the immune system; primarily used to prevent organ rejection in patients awaiting transplants. Immune suppression permits bacteria to flourish, including the bacteria that causes acne, P. acnes.
Example: Immuran


Oral Vitamin A:
Retinoids (derivatives of vitamin A) are used topically and orally to treat acne under medical supervision. Vitamin A does not treat acne. If you take excessive vitamin A, hoping that it will treat acne, your health may become worse. Remember that Vitamin A in excess quantity can have adverse effects on the body.

Hereditary:
Acne can be hereditary. If your parents had acne, you may be more prone to it.

Hormonal Changes:
Hormonal changes bring on acne. The hormone androgen is responsible for excess production of sebum. Females can have acne outbreaks during menstruation and pregnancy.

Acne-Like Conditions:
Some other conditions such as folliculitis may appear like acne. There are many other diseases that may look like acne. Some of them are rosacea, keratosis pilaris, perioral dermatitis, etc. Always visit a dermatologist instead of trying self-treatment.


Common concerns about treating acne

When treating acne as many of the factors that cause it as possible should be targeted.

Excessive sebum production: At puberty, increasing levels of androgens, the major sebotrophic hormones, begin to drive an increase in sebum production. However, while androgenic stimulation is important in the pathogenesis of acne, the typical acne patient does not have significant endocrine abnormalities. Hormonal therapy is not indicated in the initial management of mild to moderate acne, although females who require oral contraception may be candidates for anti-androgen therapy early in the course of treatment.

Abnormal desquamation of the follicular epithelium: In acne, keratinocytes, hyperproliferate and accumulate within the sebaceous follicle. As these abnormally desquamated cells accumulate in the sebaceous follicle, they lead to microcomedo formation. The microcomedo, is the precursor to all acne lesions and is present in 80% of acne papules but is invisible to the unaided eye. However, as the already clogged follicle begins to fill with lipids, bacteria and cell fragments, the microcomedo progresses to open or closed comedones (blackheads and whitehead, respectively), both of which are non-inflammatory lesions. If P. acnes proliferates, inflammatory mediators are generated and inflammatory papules and pustules occur.

Bacterial proliferation: The microenvironment of the follicle in acne is conducive to colonization with P. acnes. This leads to inflammation and the production of the visible papules and pustules with which acne patients typically present to dermatologists.

Inflammation: Inflammation in acne occurs as a result of humoral and cellular immune reactions to P. acnes proliferation. It has been suggested that changes in sebum production or composition irritate infundibular keratinocytes leading to the release of interleukin 1a (IL-1a). In addition, CD4 lymphocytes and neutrophils migrate to the follicle. Rupture of the follicular duct leads to the extravasation of lipids, corneocytes and bacteria into the dermis, causing further inflammation.

BIOSKINCARE™ is a natural skin care cream made with the same substance that a cute little creature, living under the sun, uses to bathe his own skin to protect it from environmental hazards and to repair it when damaged. On human skin the natural fluid performs three functions: a) fights opportunistic bacteria that always thrive on injured cells, b) restores a healthy skin whenever damaged by acne or other inflammatory reactions triggered by rosacea, accidents, trauma, burns, or folliculitis, boils or warts and c) moderates an otherwise strong inflammatory reaction by taking care of all the factors needed to restore skin's integrity.

BIOSKINCARE™ also keeps hair follicles opened and opens up clogged pores, vanishes post inflammatory marks quickly, destroys microbes and creates an environment that stimulates the regeneration of normal collagen. It also improves the water holding capacity of the skin and thus elasticity, density and skin firmness.

BIOSKINCARE™ contains enzymes that gently "digests" or dissolve scar tissues and damaged cells and regulate the organized production of new skin cells. It also improves skin resilience and elasticity and helps to plump the underlying structure of the skin, reducing the depth and appearance of icepick acne scars.



Last modified: November 30, 2007

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November 22, 2008

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